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Home » Products » Active Pharmaceutical Ingredients » LOSARTAN POTASSIUM

LOSARTAN POTASSIUM

LOSARTAN POTASSIUM
LOSARTAN POTASSIUM
Product Code : JRS-138
Product Description

NAME :- LOSARTAN POTASSIUM

IUPAC NAME :- [2-butyl-4-chloro-1-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1H-imidazol-5-yl]methanol

CAS NO. :- 124750-99-8

FORMULA :- C22H22CIN6O.K

SYNONYMS :- potassium[2-butyl-5-chloro-3-[[4-[2-(1,2,3-triaza-4-azanidacyclopenta-2,5-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol

APPLICATION :- Anti-hypertensive

DESCRIPTION :- Losartan Potassium is a specific antagonist of the angiotensin II receptor subtype AT1. Antagonism of the AT1 receptor and interference of association between AT1 and angiotensin II produces vasodilation and reduction of hypertension. This antagonism has other downstream effects, including a correlated antagonism of the thromboxane A2 receptor, inhibition of platelet aggregation, and induction of peroxisome proliferator-actived receptor gamma (PPARĪ³) activity.



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