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Active Pharmaceutical Ingredients

Picked up noticeable quality in the business sector as a prevalent producer, supplier and exporter, we are occupied with offering our customers with an extensive variety of Active Pharmaceutical Ingredients(APIs). Remembering the variegated prerequisites of customers, these chemicals are figured at our end to achieve their most extreme satisfaction. Besides, we guarantee to dispatch our extent on-time to the customer's destination.

To meet the requests of customers as a producer, supplier and exporter, we are occupied with offering our customers with best quality products. Handled under the direction of industrious concoction specialists, these chemicals are known for their exact structure and more time-frame of realistic usability. With a specific end goal to guarantee no dampness enters the synthetic, these are pressed in high-review bundling material.

Features:

1) Our active pharmaceutical ingredients(APIs) undergo various international regulatory processes.
2) We conduct FDA’s intensified inspection program for our products.
3) We have a good facility with flexible design capability.
4) We offer our products in bulk.
MEBEVERINE HCL
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MEBEVERINE HCL
JRS-145
Mebeverine Hcl is an anticholinergic agent which works by directly acting on smooth muscles providing its anesthetic effect. It is used to provide relief from the symptoms if irritable bowel syndrome. This compound is known to have molecular weight of 466.015 g/mol and chemical formula C25H35NO5.HCl. It is mainly administered by mouth and also has antispasmodic property. This chemical has the capability to donate 1 and accept 6 hydrogen bonds.
MECLIZINE HCL
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MECLIZINE HCL
JRS-146
Meclizine Hcl is used for the treatment of motion sickness caused symptoms including vomiting, nausea, and dizziness. It is an antihistamine agent which belongs to the group of diphenylmethylpiperazine. Also known to help in treating vertigo, this medicine is an antagonist H1 receptor having anticholinergic property and local anesthetic effects. It works by vestibular stimulation and depression of labyrinth. With the boiling point of 230 degree Celsius, it has molecular weight of 390.948 g/mol.
MEFENAMIC ACID
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MEFENAMIC ACID
JRS-148
Mefenamic Acid is used as a short term treatment to provide relief from pain resulting from various conditions and also to reduce menstrual pain & blood loss. It belongs to the anthranilic acid derivative class of NSAID drugs having protein binding capacity of up to 90%. This medicine works by preventing the formation of prostaglandins by inhibiting both isoforms of cyclooxygenase enzyme. It gets metabolized in the liver by CYP2C9.
JRS-149
Meloxicam is used to reduce swelling, pain & stiffness of joints caused during arthritis. It is known to have analgesic and antipyretic properties with excellent protein binding capacity of 99.4%. This medicine works by blocking COX enzyme which is responsible for the conversion of arachidonic acid into prostaglandin H2. It gets metabolized in the liver and has biological half life of about 20 hours with the molar mass of 351.403 g/mol.
MEMANTINE HCL
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MEMANTINE HCL
JRS-150
Memantine Hcl is a medicine which is utilized for the treatment of Alzheimer’s disease. It is the hydrochloride salt of memantine having some dopaminergic effects and is also considered as antiparkinson agent. This medicine works by inhibiting cation channels of glutamanergic NMDA receptors in central nervous system. It is orally consumed medicine having molecular weight of 215.765 g/mol and chemical formula C12H22ClN. This compound appears as fine white to off-white powder with water soluble nature.
MEPYRAMINE MALEATE
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MEPYRAMINE MALEATE
JRS-152
Mepyramine Maleate appears as white colored crystal or powder having bitter saline taste with melting point of about 100 to 101 degree Celsius. It is a histamine H1 antagonist which is used for various types of allergies including skin eruptions. This compound has chemical formula C21H27N3O5 with molar mass of 401.463 g/mol. It works by binding to the receptors present on effector cell’s surface.
MESALAMINE
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MESALAMINE
JRS-154
Mesalamine is used for the treatment of inflammatory bowel disease including inflamed anus or rectum and ulcerative colitis. It has oral or rectal routes of administration having biological half life of 5 hours after initial dose. This compound has chemical formula C7H7NO3 with molecular weight of 153.135 g/mol. It belongs to the aminosalicylates class of drugs and also has the ability to reduce swelling in the colon.
METAXALONE
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METAXALONE
JRS-155
Metaxalone is a muscle relaxant which is used for providing relief from muscle spasms. It gets metabolized in the liver by cytochrome P450 system and excreted by kidney. This compound has molecular formula C12H15NO3 and molar mass of 221.252 g/mol. It works by blocking the nerve impulses in brain and is always used together with physical therapy and rest. This medicine is known to have biological half life of up to 9.2 hours.
METFORMIN HCL
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METFORMIN HCL
JRS-156
Metformin Hcl is used to control the high blood sugar levels in patients suffering from type 2 diabetes. It is a biguanide hypoglycemic agent which works by improving insulin sensitivity and decreasing absorption of glucose in the intestine. This compound works by inhibiting NADPH: ubiquinone oxidoreductase of mitochondrial respiratory chain. It has the structural formula C4H12ClN5 and molecular weight of 165.625 g/mol. This drug is consumed by mouth and has minimal protein binding ability.
METHOCARBAMOL
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METHOCARBAMOL
JRS-157
Methocarbamol is prescribed for the treatment of skeletal muscle spasms by inhibiting carbonic anhydrase. It is a carbamate of guaifenesin having molecular formula C11H15NO5 with molar mass of 241.241 g/mol. This medicine gets metabolized in the liver with the biological half life of 1.14 to 1.24 hours. It is a central muscle relaxant which has oral and intravenous routes of administration.
METHOTREXATE
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METHOTREXATE
06
Methotrexate is a chemotherapy agent and immune system suppressant which is used for the treatment of certain types of cancer. It is known to work by inhibiting dihydrofolate reductase for cancer and by inhibiting enzymes involved in purine metabolism for rheumatoid arthritis. This compound has chemical formula C20H22N8O5 and molar mass of 454.44 g/mol. It has hepatic and intracellular metabolism. Maximum amount of this drug is excreted in urine whereas minimal amounts by feces.
METHYLENE BLUE
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METHYLENE BLUE
JRS-160
Methylene Blue is used as both a dye and a medicine. It is prescribed for the treatment of methemoglobinemia having chemical formula C16H18ClN3S and molar mass of 319.85 g/mol. This medicine is also utilized as an analgesic for the treatment of urinary tract infections. As a dye, it finds its application for endoscopic polypectomy, chromoendoscopy, Gram staining, and AFB staining procedures. It also serves as standardized Giemsa stain.
METOCLOPRAMIDE HCL
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METOCLOPRAMIDE HCL
JRS-161
Metoclopramide Hcl is used for the treatment of certain conditions of the digestive tract including stomach and intestine. It works by increasing muscle contraction and speeding up the rate of stomach emptying into the intestine. This medicine treats short term heartburn, nausea, and vomiting. In combination with and PCM, it can be prescribed to treat migraine headache. This compound has chemical formula C14H23Cl2N3O2 and molar mass of 336.257 g/mol.
MICONAZOLE NITRATE
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MICONAZOLE NITRATE
JRS-163
Miconazole Nitrate is an antifungal agent which is used for the treatment of infections caused due to fungi. It is a nitrate salt of miconazole, which is a synthetic derivative of imidazole. This compound has chemical formula C18H15Cl4N3O4 and molecular weight of 479.135 g/mol. It works by acting on fungal cell membrane and is prescribed for ringworm, jock itch, and candidiasis. This medicine is applied as a topical cream on the affected area.
JRS-165
Minoxidil is utilized for the treatment of hair loss by applying topically to the affected area. In people suffering from androgenic alopecia, it is known to be highly effective in promoting hair growth. This medicine primarily gets metabolized in the liver having biological half life of about 4.2 hours. It works by opening potassium channel and causing hyperpolarization of cell membranes. Also called as antihypertensive vasodilator medicine, it can also be availed in tablet form.
MOMETASONE FUROATE
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MOMETASONE FUROATE
JRS-167
Mometasone Furoate is prescribed for the treatment of various skin inflammatory conditions including eczema & psoriasis, hay fever, and asthma as well. It is a glucocorticoid which is administered topically or by inhalation. This medicine binds to cytoplasmic receptors and works by inhibiting cytochrome P450 2C8 enzyme. It has chemical formula C27H30O6Cl2 and molar mass of 521.4 g/mol. With the excellent protein binding capacity of 98 to 99%, it gets metabolized in the liver.
MONTELUKAST SODIUM
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MONTELUKAST SODIUM
06
Montelukast Sodium is used to reduce the number of asthma attacks and to prevent wheezing & shortness of breath. It belongs to the group of leukotriene receptor antagonists that also has the ability to decrease the use of inhaler by the patients. This medicine is metabolized in the liver by CYP2C8, CYP3A4, & CYP2C9 and excreted by the Biliary system. With 99% of protein binding ability, it is generally consumed orally.
MOSAPRIDE CITRATE
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MOSAPRIDE CITRATE
JRS-169
Mosapride Citrate is a 5HT4 agonist, which works by accelerating the gastric emptying throughout the GI tract. It is prescribed for treating irritable bowel syndrome, GRD, and functional dyspepsia. This medicine is a gastroprokinetic agent that exerts anti inflammatory effects for providing relief. It has chemical formula C27H37ClFN3O12 and molar mass of 650.05 g/mol. M1 is the major functional metabolite present in mosapride.
MOXIFLOXACIN HCL
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MOXIFLOXACIN HCL
JRS-170
Moxifloxacin Hcl is an antibiotic medicine which is used for the treatment of bacterial infections including tuberculosis, conjunctivitis, and pneumonia. It can be consumed orally as a tablet, by intravenous route, or as eye drops. This medicine is known to be highly effective against gram negative & gram positive bacteria and works by inhibiting topoisomerase type II, DNA gyrase, & topoisomerase IV, resulting in the prevention of cell replication.
MYCOPHENOLATE MOFETIL
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MYCOPHENOLATE MOFETIL
JRS-171
Mycophenolate Mofetil belongs to immunosuppressant class of drugs and is used to prevent rejection of in organ transplantation. It works by inhibiting Inosine-5’-monophosphate dehydrogenase, which is responsible for the synthesis of GMP from IMP. This medicine weakens body’s immune system for allowing it to accept new organ. It is generally given with a steroid and cyclosporine. This medicine has protein binding capacity of 82-97% with biological half life of up to 17.9 hours.
MYCOPHENOLATE SODIUM
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MYCOPHENOLATE SODIUM
06
Mycophenolate Sodium is used to allow body to accept new kidney after organ transplantation. It is an immunosuppressant which is often used in combination with other drugs. This compound has chemical formula C17H19NaO6 with molar mass of 342.323 g/mol. It prevents white blood cells from rejecting the new organ by blocking the de novo synthesis of purine nucleotides. This drug is also known to prevent the formation of antibodies from B-cells.
MECETRONIUM ETHOSULFATE
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MECETRONIUM ETHOSULFATE
jrs - 65060
Mecetronium Ethosulfate is an antiseptic agent having chemical formula C22H49NO4S with molecular weight of 423.697 g/mol. It is known to have the ability to accept 4 hydrogen bonds. This chemical finds its application in hospitals, research centers, laboratories, and veterinary sector for treating various infections. It has IUPAC name ethyl-hexadecyl-dimethylazanium.
METOPROLOL SUCCINATE
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METOPROLOL SUCCINATE
jrs - 1320
Metoprolol Succinate is used for the treatment of high blood pressure, heart problems, and angina. It is known as an adrenergic beta-1 blocking agent having antihypertensive properties. This medicine works by reducing rennin and angiotensin II secretion, resulting in decrease of sympathetic activation. It has chemical formula C34H56N2O10 and molar mass of 652.826 g/mol. This drug reduces the force & rate of myocardial contraction which results in the diminished cardiac output.
METOPROLOL TARTRATE
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METOPROLOL TARTRATE
jrs - 130656
Metoprolol Tartrate is prescribed for the treatment of hypertension to prevent stroke, high blood pressure, and kidney problems. It belongs to beta blocker class of drugs which works by reducing sodium uptake and slowing down potassium release. This medicine is also known to suppress spontaneous sarcoplasmic reticulum release which is induced by norepinephrine. With the biological half life of 3 to 7 hours, it gets metabolized in the liver by CYP2D6 and CYP3A4.
MAGNESIUM VALPROATE
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MAGNESIUM VALPROATE
JRS-142
Magnesium Valproate is a medicine which is used for the treatment of abnormal tissue growth and epilepsy condition. It is known to have anticonvulsant, antimanic, and antimigraine properties. This is a magnesium salt form of valproate acid having chemical formula C16H30MgO4 and molar mass of 310.717 g/mol. It works by inducing apoptosis, growth arrest, and tumor cell differentiation by inhibiting histone deacetylases. This drug may also increase gamma aminobutyric acid in the brain.
jrs 4160 8509
Merbromin is an antiseptic which is used to prevent infection on small cuts and abrasions. It appears as dark green colored solid which is applied topically to the affected area. This compound has chemical formula C20H8Br2HgNa2O6 with molar mass of 750.66 g/mol. It is synthesized with the combination of dibromofluorescein with sodium hydroxide and mercuric acetate. This compound works by disrupting the natural metabolism of microorganisms.
NEBIVOLOL HCL
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NEBIVOLOL HCL
JRS-179
The chemical formula of Nebivolol HCl is C22H26ClF2NO4 and the IUPAC name is 1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)-2-[[2-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)-2-hydroxyethyl]amino]ethanol; hydrochloride. It is generally used in the treatment of high blood pressure (hypertension) which prevents from various problems including strokes, heart attacks, and kidney problems. It belongs to a class of medicines called beta-blockers. The drug performs its functions by inhibiting the body parts to respond to certain natural substances such as epinephrine which results in the lowering of heart rate, and blood pressure.
NIFEDIPINE
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NIFEDIPINE
JRS-181
Nifedipine is highly recommended for the treatment of certain types of chest pain. It belongs to the family of calcium channel blockers which acts by relaxing blood vessels so that blood can flow easily. The chemical formula of the compound is C17H18N2O6 and the chemical name is dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate. It acts as a vasolidator agent and anti-anginal agent that is helpful in the lowering of blood pressure. The molecular weight of the compound is 346.339 g/mol.
NIMESULIDE
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NIMESULIDE
JRS-182
The chemical formula of Nimesulide is C13H12N2O5S and the IUPAC name is N-(4-nitro-2-phenoxyphenyl)methanesulfonamide. It possesses anti-inflammatory properties and is generally prescribed for the treatment of acute pain, osteoarthritis, and primary dysmenorrhoea in adolescents. It also shows fever reducing and pain medication properties. It belongs to the class of medicines called nonsteroidal anti-inflammatory drug (NSAID). It performs its action by blocking the production of prostaglandins and thus reducing pain and inflammation.
NITAZOXANIDE
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NITAZOXANIDE
JRS-185
Nitazoxanide is chemically known as [2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl] acetate and the chemical formula is C12H9N3O5S. It is a type of synthetic benzamide and possesses antiprotozoal properties due to which it is used against several parasitic worms and protozoa in the treatment of giardiasis and cryptosporidiosis. It acts by interfering with the pyruvate ferredoxin/flavodoxin oxidoreductase dependent electron transfer reaction, which is essential to anaerobic energy metabolism. The molar mass of the compound is 307.28 g/mol and the complexity is 428.
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