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Ajmaline Powder

Ajmaline Powder

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  • Powder
  • Ajmaline Powder

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  • 1 Days
  • HDPE DRUM

Product Description

 Ajmaline Powder

Ajmaline belonging to the ajmaline-sarpagine alkaloids is an organic chemical compound that contains indole structures ajmaline, sarpagine, or derivative. It is a plant source mainly found in the root of Rauwolfia serpentina. This agent can change the shape and threshold of cardiac action potentials. This chemical compound has potent sodium channel blocking effects and a very short half-life that makes it an effective drug for acute intravenous treatments. Many countries use this drug to treat atrial fibrillation in patients with the Wolff Parkinson White (WPW) syndrome and in well tolerated monomorphic ventricular tachycardias. For many years, the ajmaline powder has been used as a drug to challenge the conduction system of the heart in bundle branch block and syncope cases. Generally, abnormal prolongation of the HV interval is taken as an evidence of in frahisian conduction defects that lead to permanent pacemaker implantation.

NAME :- AJMALINE

IUPAC NAME:- (17R,21)-ajmalan- 17,21-diol

                         OR

(1R,9R,10S,13R,14R,16S,18S)- 13-ethyl- 8-methyl- 8,15-diazahexacyclo [14.2.1.01,9.02,7.010,15.012,17] nonadeca- 2(7),3,5-triene- 14,18-diol

CAS NO. :- 4360-12-7

FORMULA :- C20H26N2O2

SYNONYMS :- Ritmos;Ajmalin;Ignazin;Takycor;Aritmina;AJMALINE;Rytmalin;Siddiqui;Tajmalin;Cartagine

APPLICATION :- For use as an antiarrhythmic agent.

DESCRIPTION :- Ajmaline chemical compound belongs to the ajmaline-sarpagine alkaloids. These are organic compounds containing either of the indole structures ajmaline, sarpagine, or derivative thereof. An alkaloid found in the root of Rauwolfia serpentina, among other plant sources. It is a class Ia antiarrhythmic agent that apparently acts by changing the shape and threshold of cardiac action potentials. Ajmaline chemical compound produces potent sodium channel blocking effects and a very short half-life which makes it a very useful drug for acute intravenous treatments. The drug has been very popular in some countries for the treatment of atrial fibrillation in patients with the Wolff Parkinson. White syndrome and in well tolerated monomorphic ventricular tachycardias. It has also been used for many years as a drug to challenge the conduction system of the heart in cases of bundle branch block and syncope. In these cases, abnormal prolongation of the HV interval has been taken as a proof for infrahisian conduction defects tributary for permanent pacemaker implantation.

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