The chemical formula of Ajmaline is C20H26N2O2 and the IUPAC name is (17R,21)-ajmalan- 17,21-diol. It belongs to the category of alkaloids and typically used as an antiarrhythmic agent. The compound contains either the indole structures ajmaline or sarpagine and its derivatives. It is extracted from the roots of plant Rauwolfia serpentina. It is used in the treatment of acute intravenous symptoms and atrial fibrillation because of its sodium channel blocking effects.
JRS - 166
The IUPAC name of Belladonna Extract is 2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-morpholin-4-ylpyridin-3-yl]propanamide. The molecular formula of this compound is C29H29F6N3O2. It is widely used in the treatment of motion sickness, nausea, vomiting, abdominal cramping associated with menstruation, and to reduce nighttime urination. The drug also provides relief from different situations caused by Parkinson's disease including rigidity, tremor, excessive salivation, and sweating. It is also believed to control conditions such as colitis, spastic bladder, diverticulitis, infant colic, renal and biliary colic, and peptic ulcer.
JRS - 167
The IUPAC name of Berberine HCl is 9,10-Dimethoxy-5,6-dihydro[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride and the chemical formula is C20H18ClNO4. It is an important ingredient in commercial eyewash products. The chemical belongs to the family of alkaloids and is extracted from Chinese goldthread and bark of cork tree and other plants. It serves as a raw material to prepare medicines which are used in the treatment of intestinal diseases. The molar mass of the compound is 371.817 g/mol and the complexity is 488.
JRS - 168
Berberine Sulphate has the chemical formula C20H25NO11S and the IUPAC name is bis(9,10-dimethoxy-5,6-dihydro[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium) sulfate. It has many benefits on the cardiovascular system because it lowers the blood glucose level in the blood stream. The drug also acts as a herbal antidepressant and a neuroprotector against neurodegenerative disorders and congestive heart failure. It is extracted from roots and stem-barks of berberis plants. It belongs to the family of isoquinoline alkaloid and is available in bright yellow color.
JRS - 169
Berberine Tannate is available in the market as yellow or light-yellow brown powder. Its IUPAC name is 5,6-Dihydro-9,10-dimethoxybenzo[G]-1,3-benzodioxolo[5,6-A]quinolizinium and the chemical formula is C20H18NO4. It is commonly used as an antiseptic drug in the treatment of intestinal infection caused by dysentery bacillus and E.coil bacteria. The drug has a molecular weight of 336.361 g/mol and the complexity is 438. It has anti-inflammatory and anti-diabetic properties which improve intestinal health and lower cholesterol.
JRS - 170
The IUPAC name of Bergapten is 4-methoxy-7H-furo[3,2-g]chromen-7-one and the molecular formula is C12H8O4. It is generally found in bergamot and other citrus essential oils that cause phototoxicity. The chemical is also called as furocoumarins and is widely used in the preparation of fraxinol. It has a molar mass of 216.192 g/mol and the complexity is 325. The chemical can also be extracted from celery particularly the outer leaves and other grocery vegetables.
JRS - 171
The molecular formula of Bromelain is C7H3BrCINO2 and its IUPAC name is 6-bromo-5-chloro-3H-1,3-benzoxazol-2-one. It is a kind of mixture of enzymes found naturally in the juice and stems of pineapples. The enzymes are called proteolytic enzymes and are very helpful in the digestion of proteins. The compound is used for the treatment of inflammation and swelling of the nose and sinuses due to surgery or injury. It also possesses anti-inflammatory properties due to which it is utilized to treat arthritis.
Colchicine is an alkaloid which is utilized to induce polyploidy in plants. The formula is C22H25NO6 and IUPAC name is N-[(7S)-1, 2, 3, 10-tetramethoxy-9-oxo-5, 6, 7, 9-tetrahydrobenzo[a]heptalen-7-yl] acetamide. It has a molar mass of 399.437 g/mol and biological life of 26.6 to 31.2 hours. The chemical is known by its other names such as Colcrys and Mitigare. It is mainly used to treat gout, familial Mediterranean fever, pericarditis, and Behcet’s disease. It is derived from a plant called autumn crocus.
JRS - 172
Capsaicin is found as a molecular compound in spicy peppers and gives the spice factor and heat to the delicious veggies. Apart from giving spicy and bitter flavor, it is also utilized as an aid to weight loss and helps fight against cancer & chronic pain. The IUPAC name of the chemical is (6E)-N-[(4-Hydroxy-3-methoxyphenyl) methyl]-8-methylnon-6-enamide. In its purest form, it is hydrophobic, colorless, highly pungent, and crystalline to waxy compound.
The IUPAC name of Methoxsalen is 9-methoxyfuro [3, 2-g] chromen-7-one and the molecular formula is C12H8O4. It is derived from plants such as Psoralea corylifolia and Ammi majus. The drug is utilized to for treatment of several diseases including psoriasis, eczema, vitiligo, and cutaneous lymphomas. It is known by other chemical names as Xanthotoxin, Meladinine, and Puvalen. The drug has a molecular mass of 216.9 g/mol and biological half-life of about 2 hours.
JRS - 173
Noscapine Hydrochloride has the IUPAC name of 6, 7-dimethoxy-3-[(5S)-4-methoxy-6-methyl-5, 6, 7, 8-tetrahydro-[1, 3] dioxolo [4, 5-g] isoquinolin-6-ium-5-yl]-3H-2-benzofuran-1-one chloride. It is a type of naturally occurring alkaloid which has mild analgesic, antitussive, and antineoplastic activities. Its antitussive nature depresses medullary centers and suppresses cough reflex and is widely used in the treatment of bronchial asthma & pulmonary emphysema. The drug is insoluble in vegetable oils and slightly soluble in alcohol & ether.
Podophyllum Resin is extracted from the roots of plant Podophyllum. It is extensively used as paint for warts, senile keratoses, and skin neoplasms. The molecular formula is C88H92O34 and the molar mass is 1693.67 g/mol. Its strong alkaline nature destroys soft body tissues and helps in removing warts and small tumors. The keratolytic agents present in the drug softens the outermost layer of epidermis so it is used to treat corns, warts, and various skin diseases.
JRS - 174
Papain is known by its many names including Arbuz, Caroid, Nematolyt, Summetrin and Tromasin. It has the molecular formula as C45H73NO16 and is available in cream to light brown powder form. The drug has numerous benefits and uses including the treatment of animal or insect bites, infected wounds, sores, and ulcers. It is typically used as a meat tenderizer but can also be applied for pain and swelling and to remove extra fluid following trauma and surgery.
The IUPAC name of Papaverine HCl is 1-[(3, 4-dimethoxyphenyl) methyl]-6, 7-dimethoxyisoquinoline. It is available in the market by its other names such as Cardiospa, Cardovarina, Dispamil and Pavabid. It has a molar mass of 375.849 g/mol & complexity of 407 and the molecular formula is C20H22ClNO4. The drug is extensively used as smooth muscle-relaxant and in the treatment of impotence. It is able to inhibit phosphodiesterases and have straight actions on calcium channels.
JSR - 354
Piperine is extracted from peppers, herbs, and spices. It is a naturally occurring compound that mainly constitutes basic nitrogen atoms along with oxygen, sulfur, and chlorine. The IUPAC name is (2E,4E)-5-(1,3-benzodioxol-5-yl)-1-piperidin-1-ylpenta-2,4-dien-1-one and chemical formula C17H19NO3. It is available in solid form and melts at 129oC. Its complexity is 412 and the molecular weight is 285.343 g/mol. The drug shows chemopreventive, cytotoxic, anti-inflammatory, and antioxidant effects. It is also utilized as flavoring agents and food additives.
Quinine HCl is extracted from the bark of the chinchona tree. It has mild antipyretic and analgesic properties that are most commonly used in cold preparations. It has bitter & spicy taste and utilized for treating babesiosis and muscular disorders. Due to its direct effects on muscle membranes and sodium channels, it is used to treat nocturnal leg cramps and myotonia congenital. The drug has a molecular weight of 360.882 g/mol and the molecular formula is C20H25ClN2O2.
Quinine Sulphate is acknowledged by its various names including Biquintate, Strema, Surquina, and Quinsol. It has the molecular formula of C40H50N4O8S and molar mass of 746.92 g/mol. The drug is an alkaloid which is found in the extracts of chinchona tree. It is used in the treatment of malaria infections and night-time leg cramps in old people. It prevents muscle cramps by reducing the sensitivity of muscle cells to stimuli that cause them to contract.
Raubasine has the molecular formula of C21H24N2O3 and the IUPAC name is (19±)-16,17-didehydro- 19-methyloxayohimban- 16-carboxylic acid methyl ester. It is white or light yellow crystalline powder that is found naturally in plants such as Rauwolfia spp., Catharanthus roseus, and Mitragyna speciosa. It is also known by names such as Cristanyl, Lamuran, Melanex, and Sarpan. It belongs to the general class of medicines called antihypertensives and is typically used in the treatment of hypertension.
Rutin is a kind of flavonol glycoside which is found in different plants including buckwheat, forsythia, hydrangea and viola. Its chemical formula is C27H30O16 and molecular weight is 610.521 g/mol. It is basically used to reduce capillary fragility therapeutically. The drug has antiallergic, anti-inflammatory, antiproliferative, and anticarcinogenic properties and can be taken more than 1 g per day. It provides immunity against coronary heart diseases, cancers, and inflammatory bowel diseases.
Yohimbine HCl has chemical formula of C21H27ClN2O3 the IUPAC name is methyl (1S,15R,18S,19R,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate;hydrochloride . It is marketed under different brand names including Aphrodyne, Corynanthine, Pluriviron, Yocon, and Yohimex. It belongs to the category of alkaloid which possesses alpha-2-adrenergic blocking activity and is widely used as a mydriatic . The drug has a molecular weight of 390.908 g/mol. It is also utilized for the treatment of urogenital conditions and diseases such as urinary incontinence and prostatic hyperplasia.
Berberin Hydrochloride is a salt form of Berberine and is orally bioavailable. It has different properties including antineoplastics, radiosensitizing, anti-inflammatory, anti-lipidemic, and antidiabetic activities. The drug has chemical formula C20H18ClNO4 and the molecular weight is 371.817 g/mol. It belongs to the family of alkaloids and derivatives and shows neutral & weakly acidic properties. The drug modulates lipid & glucose metabolism and induces cell cycle arrest & apoptosis which stops cancer cell proliferation.