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Noscapine Hydrochloride

Noscapine Hydrochloride

800 INR/Gram

Product Details:

  • Product Type Other
  • Form Powder
  • Supply Ability : 500 Gram Per Day
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Price And Quantity

  • 350 Gram
  • 800 INR/Gram

Product Specifications

  • Powder
  • Other

Trade Information

  • 500 Gram Per Day
  • 1 Days

Product Description

 Noscapine Hydrochloride

The hydrochloride form of Noscapine is called Noscapine hydrochloride (HCL). It is regarded as analkaloid with different actions. It inhibits carbachol-stimulated phosphoinositol turnover in CNS tissues and enhances forskolin-stimulated cAMP increases. It is an antagonist at Bradykinin B Receptors (bradykinin receptors). In addition to this, Noscapine HCL binds to tubulin, arrests cells in mitosis and causes apoptosis. It blocks expansion of human leukemia and multiple myeloma cells. Furthermore, Noscapine regulates activation of IKK, suppressing the NF-B signalling pathway. While exhibiting an anti-inflammatory activity, it is an inhibitor of Tubulin.

NAME :- NOSCAPINE HCL


IUPAC NAME :- 6,7-dimethoxy-3-[(5S)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-3H-2-benzofuran-1-one chloride


CAS NO. :- 912-60-7


FORMULA :- C22H24ClNO7


SYNONYMS :- NOSCAPINEHCL;opianhydrochloride;capvalhydrochloride;lyobexhydrochloride;nsc5366hydrochloride;vadebexhydrochloride;NOSCAPINE BASE /HCL;longatinhydrochloride;coscopinhydrochloride;nectadonhydrochloride


APPLICATION :- Anti-Tussive


DESCRIPTION :- Noscapine hydrochloride is the hydrochloride form of Noscapine. Noscapine HCL is an  alkaloid with several actions. Antagonist at Bradykinin B Receptor (bradykinin receptors) (pA2 = 6.68), inhibits carbachol-stimulated phosphoinositol turnover and enhances forskolin-stimulated cAMP increases in CNS tissues. Additionally Noscapine binds to tubulin, arrests cells in mitosis and induces apoptosis. Blocks proliferation of human leukemia and multiple myeloma cells. Furthermore, Noscapine modulates IKK activation, suppressing the NF-B signaling pathway. Exhibits anti-inflammatory activity. Noscapine hydrochloride is an inhibitor of Tubulin.


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