NAME :- CHLORZOXAZONE
IUPAC NAME :- 5-chloro-3H-benzooxazol-2-one
CAS NO. :- 95-25-0
FORMULA :- C7H4CINO2
SYNONYMS :- Mioran;Miotran;Neoflex;Solaxin;Escoflex;Paraflex;Biomioran;Myoflexin;usafma-10;Myoflexine
APPLICATION :- For the relief of discomfort associated with acute painful musculoskeletal conditions.
DESCRIPTION :- Chlorzoxazone, a synthetic compound, inhibits antigen-induced bronchospasms and, hence, is used to treat asthma and allergic rhinitis. Chlorzoxazone is used as an ophthalmic solution to treat conjunctivitis and is taken orally to treat systemic mastocytosis and ulcerative colitis. Chlorzoxazone is also a centrally-acting agent for painful musculoskeletal conditions. Data available from animal experiments as well as human study indicate that chlorzoxazone acts primarily at the level of the spinal cord and subcortical areas of the brain where it inhibits multisynaptic reflex a.c. involved in producing and maintaining skeletal muscle spasm of varied etiology. The clinical result is a reduction of the skeletal muscle spasm with relief of pain and increased mobility of the involved muscles.