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DOXORUBICIN HCL

DOXORUBICIN HCL

Product Details:

  • Medicine Name DOXORUBICIN HCL
  • Type Pharmaceutical Intermediates
  • Physical Form Powder
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DOXORUBICIN HCL Price And Quantity

  • 25 Kilograms

DOXORUBICIN HCL Product Specifications

  • Powder
  • DOXORUBICIN HCL
  • Pharmaceutical Intermediates

DOXORUBICIN HCL Trade Information

  • 500 Kilograms Per Day
  • 1 Days

Product Description

NAME :- DOXORUBICIN HCL

IUPAC NAME :- (8S,10S)-10-(4-amino-5-hydroxy-6-methyl-tetrahydro-2H-pyran-2-yloxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione

CAS NO. :- 25316-40-9

FORMULA :- C27H30ClNO11

SYNONYMS :- DOX;ADR;Caely;CAELYX;fi6804;FI 106;DOX HCl;Lipodox;ADRIACIN;Ardriamycin

APPLICATION :- Antineoplastic

DESCRIPTION :- Doxorubicin hydrochloride is a DNA intercalator and powerful cytotoxic agent. Once it associates with the DNA groove, a covalent linkage forms between a DNA base and the pendant sugar of the small molecule. The intercalation into DNA blocks the replication of DNA by blocking Topo II (Topoisomerase II) This general mechanism gives it efficacy in a wide range of different cell types. Additionally, the expression of the oncogenes c-Myc and c-Jun is also down regulated by the chemical and a significant correlation was reported between the level of expression of these genes and the degree of cell growth inhibition conferred by Doxorubicin. Doxorubicin hydrochloride is an inhibitor of AMPK, TERT and POLR.

Product details 

Application

Oncology

Molecular Formula

C27H30ClNO10

IUPAC Name

(7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methox

CAS Number

20830-81-3

Application

Oncology

Molecular Formula

C27H30ClNO10

IUPAC Name

(7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methox

CAS Number

20830-81-3

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