NAME :- EFAVIRENZ
IUPAC NAME :- (4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one
CAS NO. :- 154598-52-4
FORMULA :- C14H9CIF3NO2
APPLICATION :- For use in combination treatment of HIV infection (AIDS)
DESCRIPTION :- Efavirenz (brand names SustivaÂ® and StocrinÂ®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1.For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with zidovudine or tenofovir is the preferred NNRTI-based regimen.Efavirenz is also used in combination with other antiretroviral agents as part of an expanded postexposure prophylaxis regimen to prevent HIV transmission for those exposed to materials associated with a high risk for HIV transmission.