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NIFEDIPINE

NIFEDIPINE

3975 INR/Kilograms

Product Details:

  • Medicine Name NIFEDIPINE
  • Type Pharmaceutical Intermediates
  • Physical Form Powder
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NIFEDIPINE Price And Quantity

  • 25 Kilograms
  • 3975 INR/Kilograms

NIFEDIPINE Product Specifications

  • NIFEDIPINE
  • Powder
  • Pharmaceutical Intermediates

NIFEDIPINE Trade Information

  • 500 Kilograms Per Day
  • 1 Days

Product Description

NAME :- NIFEDIPINE


IUPAC NAME :- 3,5-dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate


CAS NO. :- 21829-25-4


FORMULA :- C17H18N2O6


SYNONYMS :- Orix;Oxcord;ADALAT;Anifed;bay1040;Nifedin;Nifelan;Pidilat;Sepamit;Zenusin


APPLICATION :- For the management of vasospastic angina, chronic stable angina, hypertension, and Raynaud's phenomenon. May be used as a first line agent for left ventricular hypertrophy and isolated systolic hypertension (long-acting agents).


DESCRIPTION :- Nifedipine has been formulated as both a long- and short-acting 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nifedipine prevents calcium-dependent myocyte contraction and vasoconstriction. A second proposed mechanism for the drugs vasodilatory effects involves pH-dependent inhibition of calcium influx via inhibition of smooth muscle carbonic anhydrase. Nifedipine is used to treat hypertension and chronic stable angina.


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