IUPAC NAME :- [2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl]ethanoate
CAS NO. :- 55981-09-4
FORMULA :- C12H9N3O5S
SYNONYMS :- 2-(2'-Acetoxy)benzamido-5-nitrothiazole
APPLICATION :- For the treatment of diarrhea in adults and children caused by the protozoa Giardia lamblia and for the treatment of diarrhea in children caused by the protozoa Cryptosporidium parvum.
DESCRIPTION :- Nitazoxanide, also known by the brand name Alinia, is a synthetic nitrothiazolyl-salicylamide derivative and an anti-protozoal agent. It is approved for treatment of infectious diarrhea caused by Cryptosporidium parvum and Giardia lamblia in patients 1 year of age and older. Following oral administration it is rapidly hydrolyzed to its active metabolite, tizoxanide, which is 99% protein bound. Peak concentrations are observed 1–4 hours after administration. It is excreted in the urine, bile and feces. Untoward effects include abdominal pain, vomiting and diarrhea.