NAME :- OXYMETAZOLINE HCL
IUPAC NAME :- 6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol hydrochloride
CAS NO. :- 2315-02-8
FORMULA :- C16H24N2O HCL
SYNONYMS :- Oxymetazoline HCl; Afrazine; 2-(4-tert-butyl-3-hydroxy-2,6-dimethylbenzyl)-4,5-dihydro-1H-imidazol-3-ium
APPLICATION :- Is an Î±1-AR and Î±2-AR adrenergic receptor agonist.
DESCRIPTION :- Oxymetazoline Hydrochloride is a direct sympathomimetic agent. Is a nonselective adrenomimetic of Î±1A-AR and Î± 2A-AR (Î±1-AR and Î±2-AR adrenergic receptor) agonists. Since vascular beds widely express Î±1 receptors, the action of Oxymetazoline results in vasoconstriction due to its action on endothelial Î±2 receptors. Oxymetazoline Hydrochloride is an inhibitor of SR-2C and an activator of SR-1A, SR-1B, SR-1D and SR-2C.