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IUPAC NAME :- -4-[[(2-Amino-3,5-dibromophenyl)methyl]amino]cyclohexanol hydrochloride
CAS NO. :- 23828-92-4
FORMULA :- C13H18BR2N2O HCL
SYNONYMS :- MUCOSOLVAN;AMBROXOL HCL;AMBROXOLHYDROCLORIDE;AMBROXOLHYDROCHLORIDE(EP2001/CP2000);TRANS-4-((2-AMINO-3,5-DIBROMOBENZYL)AMINO)CYCLOHEXANOL, HCL;4-[(2-amino-3,5-dibromo-benzyl)amino]cyclohexanol hydrochloride;4-[(2-amino-3,5-dibromophenyl)methylamino]cyclohexan-1-ol hydrochloride;4-[(2-azanyl-3,5-dibromo-phenyl)methylamino]cyclohexan-1-ol hydrochloride;2-AMINO-3,5-DIBROMO-N-[TRANS-4-HYDROXYCYCLOHEXYL]BENZYLAMINE HYDROCHLORIDE;TRANS-4-[[(2-AMINO-3,5-DIBROMOPHENYL)METHYL]AMINO]CYCLOHEXANOL MONOHYDROCHLORIDE
APPLICATION :- Ambroxol is indicated as “secretolytic therapy in bronchopulmonary diseases associated with abnormal mucus secretion and impaired mucus transport. It promotes mucus clearance, facilitates expectoration and eases productive cough, allowing patients to breathe freely and deeply.
DESCRIPTION :- Ambroxol is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. The substance is a mucoactive drug with several properties including secretolytic and secretomotoric actions that restore the physiological clearance mechanisms of the respiratory tract which play an important role in the body’s natural defence mechanisms. It stimulates synthesis and release of surfactant by type II pneumocytes. Surfactants acts as an anti-glue factor by reducing the adhesion of mucus to the bronchial wall, in improving its transport and in providing protection against infection and irritating agents.